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Identification of PCPE-2 as the endogenous specific inhibitor of human BMP-1/tolloid-like proteinases
Identification of PCPE-2 as the endogenous specific inhibitor of human BMP-1/tolloid-like proteinases
来源
nature.com
类型
Technical article
语
English
发表于
十二月 04, 2023
BMP-1/tolloid-like proteinases (BTPs) are major players in tissue morphogenesis, growth and repair. They act by promoting the deposition of structural extracellular matrix proteins and by controlling the activity of matricellular proteins and TGF-β superfamily growth factors.